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Synthesis of portimines reveals the basis of their anti-cancer activity - Nature

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Synthesis of portimines reveals the basis of their anti-cancer activity - Nature

Marine-derived cyclic imine toxins, portimine A and portimine B, have attracted attention because of their chemical structure and notable anti-cancer therapeutic potential1–4. However, access to large quantities of these toxins is currently not feasible, and the molecular mechanism underlying their potent activity remains unknown until now.

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Synthesis of portimines reveals the basis of their anti-cancer activity - Nature

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Synthesis of portimines reveals the basis of their anti-cancer activity - Nature

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