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CCR2 imaging in human ST-segment elevation myocardial infarction - Nature Cardiovascular Research

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CCR2 imaging in human ST-segment elevation myocardial infarction - Nature Cardiovascular Research

Among the diverse populations of myeloid cells that reside within the healthy and diseased heart, C-C chemokine receptor type 2 (CCR2) is specifically expressed on inflammatory populations of monocytes and macrophages that contribute to the development and progression of heart failure1–4. Here, we evaluated a peptide-based imaging probe (64Cu-DOTA-ECL1i) that specifically recognizes CCR2+ monocytes and macrophages for human cardiac imaging.

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CCR2 imaging in human ST-segment elevation myocardial infarction - Nature Cardiovascular Research

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CCR2 imaging in human ST-segment elevation myocardial infarction - Nature Cardiovascular Research

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