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Unraveling the diversity of molecular glue degraders - Nature Chemical Biology

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Unraveling the diversity of molecular glue degraders - Nature Chemical Biology

By investigating the structure–activity relationship of molecular glue degraders that target cyclin K, we discovered that a wide range of compounds, including known kinase inhibitors, possess this gain-of-function activity. These findings provide insights that might enable more rational design and optimization of molecular glue compounds.

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Unraveling the diversity of molecular glue degraders - Nature Chemical Biology

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Unraveling the diversity of molecular glue degraders - Nature Chemical Biology

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