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Control of nutrient uptake by IRF4 orchestrates innate immune memory - Nature Immunology

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Control of nutrient uptake by IRF4 orchestrates innate immune memory - Nature Immunology

Natural killer (NK) cells are innate cytotoxic lymphocytes with adaptive immune features, including antigen specificity, clonal expansion and memory. As such, NK cells share many transcriptional and epigenetic programs with their adaptive CD8+ T cell siblings. Various signals ranging from antigen, co-stimulation and proinflammatory cytokines are required for optimal NK cell responses in mice and humans during virus infection; however, the integration of these signals remains unclear.

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Control of nutrient uptake by IRF4 orchestrates innate immune memory - Nature Immunology

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Control of nutrient uptake by IRF4 orchestrates innate immune memory - Nature Immunology

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