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m6A governs length-dependent enrichment of mRNAs in stress granules - Nature Structural & Molecular Biology

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m6A governs length-dependent enrichment of mRNAs in stress granules - Nature Structural & Molecular Biology

Stress granules are biomolecular condensates composed of protein and mRNA. One feature of stress granule-enriched mRNAs is that they are often longer than average. Another feature of stress granule-enriched mRNAs is that they often contain multiple N6-methyladenosine (m6A) residues. m6A is bound by the YTHDF proteins, creating mRNA–protein complexes that partition into stress granules in mammalian cells.

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m6A governs length-dependent enrichment of mRNAs in stress granules - Nature Structural & Molecular Biology

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m6A governs length-dependent enrichment of mRNAs in stress granules - Nature Structural & Molecular Biology

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