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Structure reveals why genome folding is necessary for site-specific integration of foreign DNA into CRISPR arrays - Nature Structural & Molecular Biology

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Structure reveals why genome folding is necessary for site-specific integration of foreign DNA into CRISPR arrays - Nature Structural & Molecular Biology

Bacteria and archaea acquire resistance to viruses and plasmids by integrating fragments of foreign DNA into the first repeat of a CRISPR array. However, the mechanism of site-specific integration remains poorly understood.

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Structure reveals why genome folding is necessary for site-specific integration of foreign DNA into CRISPR arrays - Nature Structural & Molecular Biology

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Structure reveals why genome folding is necessary for site-specific integration of foreign DNA into CRISPR arrays - Nature Structural & Molecular Biology

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