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Regulation with cell size ensures mitochondrial DNA homeostasis during cell growth - Nature Structural & Molecular Biology

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Regulation with cell size ensures mitochondrial DNA homeostasis during cell growth - Nature Structural & Molecular Biology

To maintain stable DNA concentrations, proliferating cells need to coordinate DNA replication with cell growth. For nuclear DNA, eukaryotic cells achieve this by coupling DNA replication to cell-cycle progression, ensuring that DNA is doubled exactly once per cell cycle. By contrast, mitochondrial DNA replication is typically not strictly coupled to the cell cycle, leaving the

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Regulation with cell size ensures mitochondrial DNA homeostasis during cell growth - Nature Structural & Molecular Biology

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Regulation with cell size ensures mitochondrial DNA homeostasis during cell growth - Nature Structural & Molecular Biology

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