Article
Mammalian CCR4–NOT binds and ubiquitinates 80S ribosomes to enforce translational stalling - Nature Structural & Molecular Biology
Rating:
0.0
Views:
92
Likes:
1
Library:
1
In vitro reconstitution of recognition of 80S ribosomes by CCR4–NOT, cryo-electron microscopy (cryoEM), crosslinking mass spectrometry and biochemical characterization reveal that CCR4–NOT specifically identifies ribosomes stalled during translation elongation. CCR4–NOT occupies the ribosomal exit site (E site) and locks the ribosomal L1 stalk in an
Rate This Post
Rate The Educational Value
Rate The Ease of Understanding and Presentation
Interesting or Boring? Rate the Entertainment Value