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Pervasive transcriptome interactions of protein-targeted drugs - Nature Chemistry

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Pervasive transcriptome interactions of protein-targeted drugs - Nature Chemistry

The off-target toxicity of drugs targeted to proteins imparts substantial health and economic costs. Proteome interaction studies can reveal off-target effects with unintended proteins; however, little attention has been paid to intracellular RNAs as potential off-targets that may contribute to toxicity.

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Pervasive transcriptome interactions of protein-targeted drugs - Nature Chemistry

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Pervasive transcriptome interactions of protein-targeted drugs - Nature Chemistry

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