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8 months ago

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Rapid resistance profiling of SARS-CoV-2 protease inhibitors - npj Antimicrobials and Resistance

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Rapid resistance profiling of SARS-CoV-2 protease inhibitors - npj Antimicrobials and Resistance

Resistance to nirmatrelvir (Paxlovid) has been shown by multiple groups and may already exist in clinical SARS-CoV-2 isolates. Here a robust cell-based assay is used to determine the relative potencies of nirmatrelvir, ensitrelvir, and FB2001 against a panel of SARS-CoV-2 main protease (Mpro) variants.

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Rapid resistance profiling of SARS-CoV-2 protease inhibitors - npj Antimicrobials and Resistance

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Rapid resistance profiling of SARS-CoV-2 protease inhibitors - npj Antimicrobials and Resistance

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Unlocking the Power of Knowledge
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Unlocking the Power of Knowledge
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