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LTP induction by structural rather than enzymatic functions of CaMKII - Nature

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LTP induction by structural rather than enzymatic functions of CaMKII - Nature

Learning and memory are thought to require hippocampal long-term potentiation (LTP), and one of the few central dogmas of molecular neuroscience that has stood undisputed for more than three decades is that LTP induction requires enzymatic activity of the Ca2+/calmodulin-dependent protein kinase II (CaMKII)1–3. However, as we delineate here, the experimental evidence is surprisingly far from conclusive.

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LTP induction by structural rather than enzymatic functions of CaMKII - Nature

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LTP induction by structural rather than enzymatic functions of CaMKII - Nature

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