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High-speed multiplane confocal microscopy for voltage imaging in densely labeled neuronal populations - Nature Neuroscience

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High-speed multiplane confocal microscopy for voltage imaging in densely labeled neuronal populations - Nature Neuroscience

Genetically encoded voltage indicators (GEVIs) hold immense potential for monitoring neuronal population activity. To date, best-in-class GEVIs rely on one-photon excitation. However, GEVI imaging of dense neuronal populations remains difficult because out-of-focus background fluorescence produces low contrast and excess noise when paired with conventional one-photon widefield imaging methods.

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High-speed multiplane confocal microscopy for voltage imaging in densely labeled neuronal populations - Nature Neuroscience

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High-speed multiplane confocal microscopy for voltage imaging in densely labeled neuronal populations - Nature Neuroscience

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