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Predicting transcriptional outcomes of novel multigene perturbations with GEARS - Nature Biotechnology

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Predicting transcriptional outcomes of novel multigene perturbations with GEARS - Nature Biotechnology

Understanding cellular responses to genetic perturbation is central to numerous biomedical applications, from identifying genetic interactions involved in cancer to developing methods for regenerative medicine. However, the combinatorial explosion in the number of possible multigene perturbations severely limits experimental interrogation.

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Predicting transcriptional outcomes of novel multigene perturbations with GEARS - Nature Biotechnology

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Predicting transcriptional outcomes of novel multigene perturbations with GEARS - Nature Biotechnology

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