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KDM6A epigenetically regulates subtype plasticity in small cell lung cancer - Nature Cell Biology

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KDM6A epigenetically regulates subtype plasticity in small cell lung cancer - Nature Cell Biology

Small cell lung cancer (SCLC) exists broadly in four molecular subtypes: ASCL1, NEUROD1, POU2F3 and Inflammatory. Initially, SCLC subtypes were thought to be mutually exclusive, but recent evidence shows intra-tumoural subtype heterogeneity and plasticity between subtypes.

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KDM6A epigenetically regulates subtype plasticity in small cell lung cancer - Nature Cell Biology

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KDM6A epigenetically regulates subtype plasticity in small cell lung cancer - Nature Cell Biology

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