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GATA2 mitotic bookmarking is required for definitive haematopoiesis - Nature Communications

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GATA2 mitotic bookmarking is required for definitive haematopoiesis - Nature Communications

In mitosis, most transcription factors detach from chromatin, but some are retained and bookmark genomic sites. Mitotic bookmarking has been implicated in lineage inheritance, pluripotency and reprogramming. However, the biological significance of this mechanism in vivo remains unclear. Here, we address mitotic retention of the hemogenic factors GATA2, GFI1B and FOS during haematopoietic specification.

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GATA2 mitotic bookmarking is required for definitive haematopoiesis - Nature Communications

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GATA2 mitotic bookmarking is required for definitive haematopoiesis - Nature Communications

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