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Hydrogen-bonded organic framework-based bioorthogonal catalysis prevents drug metabolic inactivation - Nature Catalysis

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Hydrogen-bonded organic framework-based bioorthogonal catalysis prevents drug metabolic inactivation - Nature Catalysis

Bioorthogonal chemistry provides a new avenue for disease treatment by generating therapeutic agents in situ. However, two crucial issues have to be considered for future practical applications. One is the prevention of metabolic inactivation of the in situ-synthesized drug molecules. The other is enhancing the biocompatibility and tumour cell selectivity of the bioorthogonal catalyst.

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Hydrogen-bonded organic framework-based bioorthogonal catalysis prevents drug metabolic inactivation - Nature Catalysis

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Hydrogen-bonded organic framework-based bioorthogonal catalysis prevents drug metabolic inactivation - Nature Catalysis

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