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Identification of human exTreg cells as CD16+CD56+ cytotoxic CD4+ T cells - Nature Immunology

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Identification of human exTreg cells as CD16+CD56+ cytotoxic CD4+ T cells - Nature Immunology

In atherosclerosis, some regulatory T (Treg) cells become exTreg cells. We crossed inducible Treg and exTreg cell lineage-tracker mice (FoxP3eGFP−Cre-ERT2ROSA26CAG-fl-stop-fl-tdTomato) to atherosclerosis-prone Apoe−/− mice, sorted Treg cells and exTreg cells and determined their transcriptomes by bulk RNA sequencing (RNA-seq).

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Identification of human exTreg cells as CD16+CD56+ cytotoxic CD4+ T cells - Nature Immunology

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Identification of human exTreg cells as CD16+CD56+ cytotoxic CD4+ T cells - Nature Immunology

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