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Dynamic matrices with DNA-encoded viscoelasticity for cell and organoid culture - Nature Nanotechnology

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Dynamic matrices with DNA-encoded viscoelasticity for cell and organoid culture - Nature Nanotechnology

Three-dimensional cell and organoid cultures rely on the mechanical support of viscoelastic matrices. However, commonly used matrix materials lack control over key cell-instructive properties. Here we report on fully synthetic hydrogels based on DNA libraries that self-assemble with ultrahigh-molecular-weight polymers, forming a dynamic DNA-crosslinked matrix (DyNAtrix).

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technology cloud data computing computer network software viscoelasticity cell organoid cultures nanotechnology matrices dna dynamic

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Dynamic matrices with DNA-encoded viscoelasticity for cell and organoid culture - Nature Nanotechnology

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Dynamic matrices with DNA-encoded viscoelasticity for cell and organoid culture - Nature Nanotechnology

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