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Enantioselective nickel-catalysed electrochemical cross-dehydrogenative amination - Nature Synthesis

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Enantioselective nickel-catalysed electrochemical cross-dehydrogenative amination - Nature Synthesis

Enantio-enriched amines are found in a wide range of bioactive natural products and pharmaceutical agents. However, radical-based asymmetric cross-dehydrogenative amination via electrochemical oxidative C–H/N–H coupling to facilitate catalytic C(sp3)–N bond formation remains a largely unsolved challenge in organic synthesis.

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Enantioselective nickel-catalysed electrochemical cross-dehydrogenative amination - Nature Synthesis

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Enantioselective nickel-catalysed electrochemical cross-dehydrogenative amination - Nature Synthesis

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