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Structure of an endogenous mycobacterial MCE lipid transporter - Nature

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Structure of an endogenous mycobacterial MCE lipid transporter - Nature

To replicate inside macrophages and cause tuberculosis, Mycobacterium tuberculosis must scavenge a variety of nutrients from the host1,2. The mammalian cell entry (MCE) proteins are important virulence factors in M. tuberculosis1,3, where they are encoded by large gene clusters and have been implicated in the transport of fatty acids4–7 and cholesterol1,4,8 across the impermeable mycobacterial cell envelope.

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Structure of an endogenous mycobacterial MCE lipid transporter - Nature

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Structure of an endogenous mycobacterial MCE lipid transporter - Nature

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