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Cobalt-catalysed allylic fluoroalkylation of terpenes - Nature Synthesis

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Cobalt-catalysed allylic fluoroalkylation of terpenes - Nature Synthesis

Developing practical strategies to produce high-value chemicals, such as pharmacologically active molecules, from bulk starting materials is an ongoing challenge. One potential route to this goal is the C(sp3)–H fluoroalkylation of natural products, made possible by the unique physiological properties of fluorine-containing groups. However, protocols for such fluoroalkylation remain underdeveloped.

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Cobalt-catalysed allylic fluoroalkylation of terpenes - Nature Synthesis

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Cobalt-catalysed allylic fluoroalkylation of terpenes - Nature Synthesis

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