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10 months ago

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Effect of posttranslational modifications and subclass on IgG activity: from immunity to immunotherapy - Nature Immunology

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Effect of posttranslational modifications and subclass on IgG activity: from immunity to immunotherapy - Nature Immunology

Humoral immune responses are characterized by complex mixtures of polyclonal antibody species varying in their isotype, target epitope specificity and affinity. Posttranslational modifications occurring during antibody production in both the antibody variable and constant domain create further complexity and can modulate antigen specificity and antibody Fc-dependent effector functions, respectively.

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Effect of posttranslational modifications and subclass on IgG activity: from immunity to immunotherapy - Nature Immunology

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Effect of posttranslational modifications and subclass on IgG activity: from immunity to immunotherapy - Nature Immunology

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