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Cartilage-like protein hydrogels engineered via entanglement - Nature

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Cartilage-like protein hydrogels engineered via entanglement - Nature

Load-bearing tissues, such as muscle and cartilage, exhibit high elasticity, high toughness and fast recovery, but have different stiffness (with cartilage being significantly stiffer than muscle)1–8. Muscle achieves its toughness through finely controlled forced domain unfolding–refolding in the muscle protein titin, whereas articular cartilage achieves its high stiffness and toughness through an entangled network comprising collagen and proteoglycans.

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Cartilage-like protein hydrogels engineered via entanglement - Nature

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Cartilage-like protein hydrogels engineered via entanglement - Nature

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