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Histone demethylase KDM5D upregulation drives sex differences in colon cancer - Nature

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Histone demethylase KDM5D upregulation drives sex differences in colon cancer - Nature

Sex exerts a profound impact on cancer incidence, spectrum and outcomes, yet the molecular and genetic bases of such sex differences are ill-defined and presumptively ascribed to X-chromosome genes and sex hormones1. Such sex differences are particularly prominent in colorectal cancer (CRC) in which men experience higher metastases and mortality.

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Histone demethylase KDM5D upregulation drives sex differences in colon cancer - Nature

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Histone demethylase KDM5D upregulation drives sex differences in colon cancer - Nature

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