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Sequential and directional insulation by conserved CTCF sites underlies the Hox timer in stembryos - Nature Genetics

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Sequential and directional insulation by conserved CTCF sites underlies the Hox timer in stembryos - Nature Genetics

During development, Hox genes are temporally activated according to their relative positions on their clusters, contributing to the proper identities of structures along the rostrocaudal axis. To understand the mechanism underlying this Hox timer, we used mouse embryonic stem cell-derived stembryos.

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Sequential and directional insulation by conserved CTCF sites underlies the Hox timer in stembryos - Nature Genetics

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Sequential and directional insulation by conserved CTCF sites underlies the Hox timer in stembryos - Nature Genetics

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