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Molecular mechanisms of gasdermin D pore-forming activity - Nature Immunology

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Molecular mechanisms of gasdermin D pore-forming activity - Nature Immunology

The regulated disruption of the plasma membrane, which can promote cell death, cytokine secretion or both is central to organismal health. The protein gasdermin D (GSDMD) is a key player in this process. GSDMD forms membrane pores that can promote cytolysis and the release of interleukin-1 family cytokines into the extracellular space.

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Molecular mechanisms of gasdermin D pore-forming activity - Nature Immunology

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Molecular mechanisms of gasdermin D pore-forming activity - Nature Immunology

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