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11 months ago

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Genome control by SMC complexes - Nature Reviews Molecular Cell Biology

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Genome control by SMC complexes - Nature Reviews Molecular Cell Biology

Many cellular processes require large-scale rearrangements of chromatin structure. Structural maintenance of chromosomes (SMC) protein complexes are molecular machines that can provide structure to chromatin. These complexes can connect DNA elements in cis, walk along DNA, build and processively enlarge DNA loops and connect DNA molecules in trans to hold together the sister chromatids.

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Genome control by SMC complexes - Nature Reviews Molecular Cell Biology

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Genome control by SMC complexes - Nature Reviews Molecular Cell Biology

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