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TGF-β controls development of TCRγδ+CD8αα+ intestinal intraepithelial lymphocytes - Cell Discovery

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TGF-β controls development of TCRγδ+CD8αα+ intestinal intraepithelial lymphocytes - Cell Discovery

γδ intestinal intraepithelial lymphocytes (IELs) constitute the majority of IELs with unique CD8αα+ homodimers that are distinct from γδT cells in other tissues. However, it remains largely unclear how those cells develop.

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TGF-β controls development of TCRγδ+CD8αα+ intestinal intraepithelial lymphocytes - Cell Discovery

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TGF-β controls development of TCRγδ+CD8αα+ intestinal intraepithelial lymphocytes - Cell Discovery

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