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Disruption of locus coeruleus-related functional networks in Parkinson's disease - npj Parkinson's Disease

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Disruption of locus coeruleus-related functional networks in Parkinson's disease - npj Parkinson's Disease

Locus coeruleus (LC) is severely affected in Parkinson's Disease (PD). However, alterations in LC-related resting-state networks (RSNs) in PD remain unclear. We used resting-state functional MRI to investigate the alterations in functional connectivity (FC) of LC-related RSNs and the associations between RSNs changes and clinical features in idiopathic rapid eye movement sleep behavior disorder (iRBD) and PD patients with (PDRBD+) and without RBD (PDRBD−).

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Disruption of locus coeruleus-related functional networks in Parkinson's disease - npj Parkinson's Disease

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Disruption of locus coeruleus-related functional networks in Parkinson's disease - npj Parkinson's Disease

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