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Ageing restructures the transcriptome of the hypothalamic supraoptic nucleus and alters the response to dehydration - npj Aging

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Ageing restructures the transcriptome of the hypothalamic supraoptic nucleus and alters the response to dehydration - npj Aging

Ageing is associated with altered neuroendocrine function. In the context of the hypothalamic supraoptic nucleus, which makes the antidiuretic hormone vasopressin, ageing alters acute responses to hyperosmotic cues, rendering the elderly more susceptible to dehydration. Chronically, vasopressin has been associated with numerous diseases of old age, including type 2 diabetes and metabolic syndrome.

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Ageing restructures the transcriptome of the hypothalamic supraoptic nucleus and alters the response to dehydration - npj Aging

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Ageing restructures the transcriptome of the hypothalamic supraoptic nucleus and alters the response to dehydration - npj Aging

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