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Gut microbiota and circadian rhythm in Alzheimer's disease pathophysiology: a review and hypothesis on their association - npj Aging
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Alzheimer's disease (AD) is the most common neurodegenerative disease and the leading cause of dementia worldwide. Different pathologic changes have been introduced to be involved in its progression. Although amyloid-β (Aβ) deposition and tau hyperphosphorylation and aggregation are mainly considered the main characterizations of AD, several other processes are involved.
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