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11 months ago

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Stress response in tumor-infiltrating T cells is linked to immunotherapy resistance - Nature Medicine

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Stress response in tumor-infiltrating T cells is linked to immunotherapy resistance - Nature Medicine

A newly composed single-cell transcriptomic atlas of tumor-infiltrating T cells across 16 cancer types revealed previously undescribed T cell states and heterogeneity. A unique T cell stress response state, TSTR, was linked to immunotherapy resistance. Our high-resolution T cell reference maps, web portal, and annotation tool can assist efforts to develop T cell therapies.

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Stress response in tumor-infiltrating T cells is linked to immunotherapy resistance - Nature Medicine

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Stress response in tumor-infiltrating T cells is linked to immunotherapy resistance - Nature Medicine

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