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Amplifying gene expression with RNA-targeted therapeutics - Nature Reviews Drug Discovery

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Amplifying gene expression with RNA-targeted therapeutics - Nature Reviews Drug Discovery

Many diseases are caused by insufficient expression of mutated genes and would benefit from increased expression of the corresponding protein. However, in drug development, it has been historically easier to develop drugs with inhibitory or antagonistic effects. Protein replacement and gene therapy can achieve the goal of increased protein expression but have limitations.

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Amplifying gene expression with RNA-targeted therapeutics - Nature Reviews Drug Discovery

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Amplifying gene expression with RNA-targeted therapeutics - Nature Reviews Drug Discovery

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