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Establishment of gastrointestinal assembloids to study the interplay between epithelial crypts and their mesenchymal niche - Nature Communications

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Establishment of gastrointestinal assembloids to study the interplay between epithelial crypts and their mesenchymal niche - Nature Communications

The cellular organization of gastrointestinal crypts is orchestrated by different cells of the stromal niche but available in vitro models fail to fully recapitulate the interplay between epithelium and stroma. Here, we establish a colon assembloid system comprising the epithelium and diverse stromal cell subtypes.

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Establishment of gastrointestinal assembloids to study the interplay between epithelial crypts and their mesenchymal niche - Nature Communications

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Establishment of gastrointestinal assembloids to study the interplay between epithelial crypts and their mesenchymal niche - Nature Communications

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