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A look into the dynamic process of proofreading in DNA polymerase-γ at near-atomic resolution - Nature Structural & Molecular Biology

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A look into the dynamic process of proofreading in DNA polymerase-γ at near-atomic resolution - Nature Structural & Molecular Biology

The correction of errors during mitochondrial DNA replication by the proofreading function of DNA polymerase-γ is crucial for maintaining the integrity of the mitochondrial genome and the production of cellular energy. Using cryo-electron microscopy, several steps of the DNA polymerase-γ proofreading pathway have been revealed at near-atomic resolution.

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A look into the dynamic process of proofreading in DNA polymerase-γ at near-atomic resolution - Nature Structural & Molecular Biology

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A look into the dynamic process of proofreading in DNA polymerase-γ at near-atomic resolution - Nature Structural & Molecular Biology

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