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Multi-site programmable functionalization of alkenes via controllable alkene isomerization - Nature Chemistry

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Multi-site programmable functionalization of alkenes via controllable alkene isomerization - Nature Chemistry

Direct and selective functionalization of hydrocarbon chains is a fundamental problem in synthetic chemistry. Conventional functionalization of C=C double bonds and C(sp3)–H bonds provides some solutions, but site diversity remains an issue. The merging of alkene isomerization with (oxidative) functionalization provides an ideal method for remote functionalization, which would provide more opportunities for site diversity.

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Multi-site programmable functionalization of alkenes via controllable alkene isomerization - Nature Chemistry

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Multi-site programmable functionalization of alkenes via controllable alkene isomerization - Nature Chemistry

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