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ARG1-expressing microglia show a distinct molecular signature and modulate postnatal development and function of the mouse brain - Nature Neuroscience

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ARG1-expressing microglia show a distinct molecular signature and modulate postnatal development and function of the mouse brain - Nature Neuroscience

Molecular diversity of microglia, the resident immune cells in the CNS, is reported. Whether microglial subsets characterized by the expression of specific proteins constitute subtypes with distinct functions has not been fully elucidated. Here we describe a microglial subtype expressing the enzyme arginase-1 (ARG1; that is, ARG1+ microglia) that is found predominantly in the basal forebrain and ventral striatum during early postnatal mouse development.

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ARG1-expressing microglia show a distinct molecular signature and modulate postnatal development and function of the mouse brain - Nature Neuroscience

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ARG1-expressing microglia show a distinct molecular signature and modulate postnatal development and function of the mouse brain - Nature Neuroscience

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