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Two-component molecular motor driven by a GTPase cycle - Nature Physics

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Two-component molecular motor driven by a GTPase cycle - Nature Physics

ATPases are a group of enzymes that can cyclically convert the free energy of ATP hydrolysis into mechanical work. GTPases are another class of enzymes that are predominantly associated with signal transduction processes, but their role in mechanotransduction is less established. It was previously shown that the binding of the GTPase Rab5 to the tethering protein EEA1 induces a large conformational change in EEA1 from a rigid, extended to a flexible, collapsed state.

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Two-component molecular motor driven by a GTPase cycle - Nature Physics

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Two-component molecular motor driven by a GTPase cycle - Nature Physics

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