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Increased activity of lacrimal gland mast cells are associated with corneal epitheliopathy in aged mice - npj Aging

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Increased activity of lacrimal gland mast cells are associated with corneal epitheliopathy in aged mice - npj Aging

The lacrimal gland undergoes significant structural and functional deterioration with aging. Marked with increased inflammation and fibrosis, the aged lacrimal gland is unable to perform its protective function. As a result, the ocular surface becomes highly susceptible to various ocular surface pathologies, including corneal epitheliopathy. We and others have previously shown that mast cells mediate tissue inflammation by recruiting other immune cells.

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Increased activity of lacrimal gland mast cells are associated with corneal epitheliopathy in aged mice - npj Aging

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Increased activity of lacrimal gland mast cells are associated with corneal epitheliopathy in aged mice - npj Aging

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