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Circadian rhythm biomarker from wearable device data is related to concurrent antidepressant treatment response - npj Digital Medicine

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Circadian rhythm biomarker from wearable device data is related to concurrent antidepressant treatment response - npj Digital Medicine

Major depressive disorder (MDD) is associated with circadian rhythm disruption. Yet, no circadian rhythm biomarkers have been clinically validated for assessing antidepressant response. In this study, 40 participants with MDD provided actigraphy data using wearable devices for one week after initiating antidepressant treatment in a randomized, double-blind, placebo-controlled trial. Their depression severity was calculated pretreatment, after one week and eight weeks of treatment.

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Circadian rhythm biomarker from wearable device data is related to concurrent antidepressant treatment response - npj Digital Medicine

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Circadian rhythm biomarker from wearable device data is related to concurrent antidepressant treatment response - npj Digital Medicine

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