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Regulation of synaptic connectivity in schizophrenia spectrum by mutual neuron-microglia interaction - Communications Biology

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Regulation of synaptic connectivity in schizophrenia spectrum by mutual neuron-microglia interaction - Communications Biology

The examination of post-mortem brain tissue suggests synaptic loss as a central pathological hallmark of schizophrenia spectrum (SCZ), which is potentially related to activated microglia and increased inflammation. Induced pluripotent stem cells serve as a source for neurons and microglia-like cells to address neuron-microglia interactions.

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Regulation of synaptic connectivity in schizophrenia spectrum by mutual neuron-microglia interaction - Communications Biology

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Regulation of synaptic connectivity in schizophrenia spectrum by mutual neuron-microglia interaction - Communications Biology

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