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Characterizing expression changes in noncoding RNAs during aging and heterochronic parabiosis across mouse tissues - Nature Biotechnology

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Characterizing expression changes in noncoding RNAs during aging and heterochronic parabiosis across mouse tissues - Nature Biotechnology

Molecular mechanisms of organismal and cell aging remain incompletely understood. We, therefore, generated a body-wide map of noncoding RNA (ncRNA) expression in aging (16 organs at ten timepoints from 1 to 27 months) and rejuvenated mice. We found molecular aging trajectories are largely tissue-specific except for eight broadly deregulated microRNAs (miRNAs).

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Characterizing expression changes in noncoding RNAs during aging and heterochronic parabiosis across mouse tissues - Nature Biotechnology

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Characterizing expression changes in noncoding RNAs during aging and heterochronic parabiosis across mouse tissues - Nature Biotechnology

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