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Immune modulation by MANF improves regeneration in aged skeletal muscle - Nature Aging

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Immune modulation by MANF improves regeneration in aged skeletal muscle - Nature Aging

Despite the central role of immune regulation in tissue repair, the contribution of immune dysfunction to regenerative failure in aging is mostly unknown. We discovered a mechanism of immune modulation that operates during skeletal muscle regeneration that is compromised in aged animals and can be harnessed to improve regenerative capacity in aging.

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Immune modulation by MANF improves regeneration in aged skeletal muscle - Nature Aging

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Immune modulation by MANF improves regeneration in aged skeletal muscle - Nature Aging

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