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Cryo-electron microscopy structures of capsids and in situ portals of DNA-devoid capsids of human cytomegalovirus - Nature Communications

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Cryo-electron microscopy structures of capsids and in situ portals of DNA-devoid capsids of human cytomegalovirus - Nature Communications

The portal-scaffold complex is believed to nucleate the assembly of herpesvirus procapsids. During capsid maturation, two events occur: scaffold expulsion and DNA incorporation. The portal-scaffold interaction and the conformational changes that occur to the portal during the different stages of capsid formation have yet to be elucidated structurally. Here we present high-resolution structures of the A- and B-capsids and in-situ portals of human cytomegalovirus.

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Cryo-electron microscopy structures of capsids and in situ portals of DNA-devoid capsids of human cytomegalovirus - Nature Communications

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Cryo-electron microscopy structures of capsids and in situ portals of DNA-devoid capsids of human cytomegalovirus - Nature Communications

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