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Membrane phase separation drives responsive assembly of receptor signaling domains - Nature Chemical Biology

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Membrane phase separation drives responsive assembly of receptor signaling domains - Nature Chemical Biology

Plasma membrane heterogeneity has been tied to a litany of cellular functions and is often explained by analogy to membrane phase separation; however, models based on phase separation alone fall short of describing the rich organization available within cell membranes. Here we present comprehensive experimental evidence motivating an updated model of plasma membrane heterogeneity in which membrane domains assemble in response to protein scaffolds.

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Membrane phase separation drives responsive assembly of receptor signaling domains - Nature Chemical Biology

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Membrane phase separation drives responsive assembly of receptor signaling domains - Nature Chemical Biology

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