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Control of transcription elongation and DNA repair by alarmone ppGpp - Nature Structural & Molecular Biology

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Control of transcription elongation and DNA repair by alarmone ppGpp - Nature Structural & Molecular Biology

Second messenger (p)ppGpp (collectively guanosine tetraphosphate and guanosine pentaphosphate) mediates bacterial adaptation to nutritional stress by modulating transcription initiation. More recently, ppGpp has been implicated in coupling transcription and DNA repair; however, the mechanism of ppGpp engagement remained elusive.

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Control of transcription elongation and DNA repair by alarmone ppGpp - Nature Structural & Molecular Biology

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Control of transcription elongation and DNA repair by alarmone ppGpp - Nature Structural & Molecular Biology

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