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Discrimination between cyclic nucleotides in a cyclic nucleotide-gated ion channel - Nature Structural & Molecular Biology

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Discrimination between cyclic nucleotides in a cyclic nucleotide-gated ion channel - Nature Structural & Molecular Biology

Cyclic nucleotide-gated ion channels are crucial in many physiological processes such as vision and pacemaking in the heart. SthK is a prokaryotic homolog with high sequence and structure similarities to hyperpolarization-activated and cyclic nucleotide-modulated and cyclic nucleotide-gated channels, especially at the level of the cyclic nucleotide binding domains (CNBDs).

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Discrimination between cyclic nucleotides in a cyclic nucleotide-gated ion channel - Nature Structural & Molecular Biology

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Discrimination between cyclic nucleotides in a cyclic nucleotide-gated ion channel - Nature Structural & Molecular Biology

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