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Immunoglobulin M perception by FcμR - Nature

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Immunoglobulin M perception by FcμR - Nature

Immunoglobulin M (IgM) is the first antibody to emerge during embryonic development and the humoral immune response1. IgM can exist in several distinct forms, including monomeric, membrane-bound IgM within the B cell receptor (BCR) complex, pentameric and hexameric IgM in serum and secretory IgM on the mucosal surface. FcμR, the only IgM-specific receptor in mammals, recognizes different forms of IgM to regulate diverse immune responses2–5.

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Immunoglobulin M perception by FcμR - Nature

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Immunoglobulin M perception by FcμR - Nature

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