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The implication of Mycobacterium tuberculosis-mediated metabolism of targeted xenobiotics - Nature Reviews Chemistry

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The implication of Mycobacterium tuberculosis-mediated metabolism of targeted xenobiotics - Nature Reviews Chemistry

Drug metabolism is generally associated with liver enzymes. However, in the case of Mycobacterium tuberculosis (Mtb), the causative agent of tuberculosis (TB), Mtb-mediated drug metabolism plays a significant role in treatment outcomes. Mtb is equipped with enzymes that catalyse biotransformation reactions on xenobiotics with consequences either in its favour or as a hindrance by deactivating or activating chemical entities, respectively.

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The implication of Mycobacterium tuberculosis-mediated metabolism of targeted xenobiotics - Nature Reviews Chemistry

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The implication of Mycobacterium tuberculosis-mediated metabolism of targeted xenobiotics - Nature Reviews Chemistry

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