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The X-linked epigenetic regulator UTX controls NK cell-intrinsic sex differences - Nature Immunology

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The X-linked epigenetic regulator UTX controls NK cell-intrinsic sex differences - Nature Immunology

Viral infection outcomes are sex biased, with males generally more susceptible than females. Paradoxically, the numbers of antiviral natural killer (NK) cells are increased in males. We demonstrate that while numbers of NK cells are increased in male mice, they display decreased effector function compared to females in mice and humans. These differences were not solely dependent on gonadal hormones, because they persisted in gonadectomized mice.

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The X-linked epigenetic regulator UTX controls NK cell-intrinsic sex differences - Nature Immunology

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The X-linked epigenetic regulator UTX controls NK cell-intrinsic sex differences - Nature Immunology

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